Ornithine, a nonessential amino acid, is produced in the body in the form of Arginine. Through a balanced and healthy diet, the body can produce sufficient supplies of Ornithine, although it is also taken as a dietary supplement.
Ornithine is known to be effective in increasing the rate of fat burning, preventing heart disease and arthritis, aiding wound healing, and reducing cholesterol.
By stimulating hormones, such as insulin and growth hormone, Ornithine regulates immune system and liver function while promoting the metabolization of body fat. The stimulation of growth hormone in the pituitary has also been shown to aid wound healing. In the prevention of heart disease, Ornithine reduces cholesterol and fatty deposits in arteries.
Ornithine is metabolized into Arginine, and vice versa, in the urea cycle. While these amino acids have similar effects, Ornithine is twice as effective.
Studies have shown that equal parts of Arginine and Ornithine taken daily can increase total strength and lean body mass.
Insufficient levels of Ornithine may result in birth defects and delayed maturation. A number of conditions may arise that negatively affect the natural production of Ornithine, including rare genetic disorders and high stress and trauma conditions that impair the synthesis of Ornithine.
Ornithine can be obtained through dietary sources, including meats, dairy products, soybeans, white/wheat flour, gelatin, wheat, oats, coconuts, peanuts, walnuts, chocolate and carob.
It is recommended that Ornithine be taken in balance with other amino acids. For an adult, the daily required dosage is 500 mg to 2 grams. Doses higher than 10 grams daily may result in adverse reactions, such as nausea and abdominal cramps. To promote healing, two parts Arginine and one part Ornithine is suggested. The metabolism of amino acids may be improved by combining them with other nutrient supplements, such as B6, zinc, manganese and magnesium.
High levels of Ornithine may result in seizures and gyrate atrophy, resulting in diminished vision, cataracts, and night blindness. Treatment of diseases with Ornithine should only be done under a doctor’s supervision.
References:* Balch, James F. and Phyllis A. Balch,, Prescription for Nutritional Healing: A to Z, Guide to Supplements, Avery Publishing 2000.
Braverman, Eric P., The Healing Nutrients, Within, Keats Publishing, 1997.
Sahley, Billie J. and Katherine M. Birkner, Heal, with Amino Acids, Pain & Stress Publications,2000
