Valine is an essential amino acid that helps stimulate the central nervous system and promote proper mental functioning. A branched-chain amino acid (BCAA), it is found in fibrous protein abundant in bones, cartilage and other connective tissues, and in high concentration in muscle tissue. Together with the other BCAAs, isoleucine and leucine, Valine works to promote normal growth, repair tissues, regulate blood sugar, and provide the body with energy.
Valine works to maintain muscle tissue and the store of glycogen, promote protein synthesis, serve as substrates for gluconeogenesis and provide energy to skeletal muscles during times of stress. In treatments, valine sometimes is used in the management of burns and hepatic encephalopathy. They are also applied in trauma treatment due to their ability to promote protein synthesis and prevent muscle catabolism.
Specifically, Valine contributes to stress reduction, energy and muscle metabolism, tissue repair and the synthesis of glucose in the liver. In treatments, Valine has been found useful in treating muscle, mental and emotional disorders, insomnia, nervousness, ammonia toxicity and amino acid deficiencies from drug addiction.
Valine deficiency can result in a deterioration of muscle function and mental health, insomnia and skin hypersensitivity. Symptoms may include a higher susceptibility to allergens, loss of balance and a deterioration in muscle function. An inability to metabolize valine, leucine and isoleucine is known to cause Maple syrup urine disease (MSUD).
Valine, which can only be obtained through dietary sources, can be found in meats, fish, dairy products, grains, soy protein, peanuts and vegetables, such as mushrooms.
Daily required dosages per kilogram of body weight are as follows: Adults 5 mg, Young adults 23 mg, Children 5 mg, and Infants 89 mg. The metabolism of BCAAs may be improved by combining them with other nutrient supplements, such as B12 and biotin.
References:
“L-Valine”Electronicsource.http://www.vitaminstuff.com, * “Valine” Electronic source. http://www.vitamins-supplements.org * “Branched-Chain AminoAcid” Electronic source http://www.pdrhealth.com/
